Hiroyuki Osada Selected Research

Melanins (Melanin)

3/2022	Identification of Scytalone Dehydratase Inhibitors Effective against Melanin Biosynthesis Dehydratase Inhibitor-Resistant Pyricularia oryzae.
12/2021	Biosynthesis and biological function of secondary metabolites of the rice blast fungus Pyricularia oryzae.

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Hiroyuki Osada Research Topics

Disease

81	Neoplasms (Cancer) 06/2023 - 01/2003
12	Infections 08/2022 - 08/2005
12	Neoplasm Metastasis (Metastasis) 10/2021 - 04/2003
6	Carcinogenesis 04/2023 - 10/2004
6	Breast Neoplasms (Breast Cancer) 01/2021 - 12/2003
6	Carcinoma (Carcinomatosis) 04/2017 - 12/2003
5	Inflammation (Inflammations) 01/2022 - 10/2002
4	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 12/2015
4	Prostatic Neoplasms (Prostate Cancer) 06/2023 - 10/2008
4	Fibrosarcoma 01/2023 - 05/2004
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 01/2016
4	Bone Resorption 09/2021 - 03/2006
3	Hypoxia (Hypoxemia) 01/2023 - 12/2019
3	Obesity 10/2022 - 08/2009
3	Body Weight (Weight, Body) 10/2022 - 09/2013
3	Osteoporosis 09/2021 - 03/2006
3	Malaria 01/2021 - 01/2015
3	Hepatocellular Carcinoma (Hepatoma) 04/2017 - 02/2004
3	Leukemia 12/2014 - 10/2004
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2007 - 05/2003
2	Necrosis 12/2023 - 03/2006
2	Neuroblastoma 12/2021 - 09/2004
2	Periodontal Diseases (Periodontal Disease) 09/2021 - 11/2015
2	Periodontitis 09/2021 - 11/2015
2	Alveolar Bone Loss 09/2021 - 11/2015
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 08/2009
2	Virus Diseases (Viral Diseases) 12/2014 - 04/2011
2	Vaccinia 04/2011 - 08/2002
2	Lung Neoplasms (Lung Cancer) 08/2008 - 12/2005
1	Adenocarcinoma of Lung 02/2024
1	Amyloid Plaque 10/2023
1	Cystic Fibrosis (Mucoviscidosis) 01/2023

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 06/2023 - 04/2003
9	reveromycin AIBA 01/2021 - 10/2002
7	heparanaseIBA 09/2008 - 04/2003
6	Heparitin Sulfate (Heparan Sulfate)IBA 08/2007 - 04/2003
4	EnzymesIBA 01/2023 - 02/2004
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 03/2006
4	Antimalarials (Antimalarial Agents)IBA 01/2023 - 05/2015
4	OsteoprotegerinIBA 09/2021 - 09/2013
4	Diphosphonates (Bisphosphonates)IBA 05/2020 - 08/2008
4	GlucuronidaseIBA 09/2004 - 04/2003
3	Hormones (Hormone)IBA 06/2023 - 12/2013
3	Transcription Factors (Transcription Factor)IBA 04/2023 - 11/2020
3	Messenger RNA (mRNA)IBA 04/2022 - 04/2003
3	Peptides (Polypeptides)IBA 01/2022 - 10/2004
3	Amino Acids FDA Link 01/2022 - 01/2006
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 12/2019
3	Phosphotransferases (Kinase)IBA 01/2017 - 02/2003
3	Matrix Metalloproteinases (MMPs)IBA 01/2015 - 08/2005
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2013 - 12/2005
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 02/2024 - 09/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2024 - 09/2011
2	CaspasesIBA 12/2023 - 01/2013
2	RNA (Ribonucleic Acid)IBA 06/2023 - 01/2021
2	Antineoplastic Agents (Antineoplastics)IBA 04/2023 - 04/2008
2	Dihydroorotate DehydrogenaseIBA 01/2023 - 11/2021
2	ChromatinIBA 01/2023 - 01/2021
2	pyrimidineIBA 01/2023 - 11/2021
2	Blood Glucose (Blood Sugar)IBA 10/2022 - 01/2020
2	LectinsIBA 08/2022 - 06/2012
2	Melanins (Melanin)IBA 03/2022 - 12/2021
2	Glutathione (Reduced Glutathione)IBA 01/2022 - 10/2014
2	Tenuazonic AcidIBA 12/2021 - 12/2021
2	MycotoxinsIBA 12/2021 - 03/2009
2	CytokinesIBA 10/2021 - 11/2015
2	Oxygen (Dioxygen)IBA 10/2021 - 01/2008
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2012
2	CateninsIBA 01/2020 - 04/2017
2	LigandsIBA 01/2019 - 01/2018
2	NucleoproteinsIBA 01/2017 - 04/2010
2	Antiviral Agents (Antivirals)IBA 01/2017 - 07/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 01/2015
2	TubulinIBA 05/2015 - 03/2007
2	DiketopiperazinesIBA 06/2012 - 03/2009
2	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 02/2009 - 08/2005
2	Glycoproteins (Glycoprotein)IBA 02/2009 - 08/2005
2	tryprostatin AIBA 04/2008 - 12/2003
2	Fas Ligand Protein (Fas Ligand)IBA 10/2005 - 03/2004
2	PerforinIBA 10/2005 - 03/2004
2	phosmidosineIBA 10/2004 - 01/2003
2	GlycosaminoglycansIBA 09/2004 - 03/2004
2	Angiogenesis InhibitorsIBA 07/2004 - 07/2004
2	p38 Mitogen-Activated Protein KinasesIBA 02/2003 - 10/2002
1	alantolactoneIBA 02/2024
1	necrostatin-1IBA 12/2023
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 12/2023
1	1,2,3,4-tetrahydroisoquinolineIBA 10/2023
1	PropionatesIBA 10/2023
1	Amyloid beta-PeptidesIBA 10/2023
1	Androgen Receptors (Androgen Receptor)IBA 06/2023
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 06/2023
1	Long Noncoding RNAIBA 06/2023
1	AndrogensIBA 06/2023
1	Galactose (Galactopyranose)FDA LinkGeneric 05/2023
1	oligomycin sensitivity-conferring protein (complex V)IBA 01/2023
1	allantopyrone AIBA 01/2023

Therapy/Procedure

17	Therapeutics 06/2023 - 07/2004
9	Drug Therapy (Chemotherapy) 01/2023 - 12/2003
2	Ligation 11/2015 - 03/2006